Hume, Alistair

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近期论文

HUME AN, 2015. Myosin–a monarch of pigment transport? Pigment cell & melanoma research. 28(2), 126-7 TARAFDER AK, BOLASCO G, CORREIA MS, PEREIRA FJC, IANNONE L, HUME AN, KIRKPATRICK N, PICARDO M, TORRISI MR, RODRIGUES IP, RAMALHO JS, FUTTER CE, BARRAL DC and SEABRA MC, 2014. Rab11b mediates melanin transfer between donor melanocytes and acceptor keratinocytes via coupled exo/endocytosis. The Journal of investigative dermatology. 134(4), 1056-66 BOOTH AEG, TARAFDER AK, HUME AN, RECCHI C and SEABRA MC, 2014. A Role for Na+,K+-ATPase α1 in Regulating Rab27a Localisation on Melanosomes. PloS one. 9(7), e102851 EVANS RD, ROBINSON C, BRIGGS DA, TOOTH DJ, RAMALHO JS, CANTERO M, MONTOLIU L, PATEL S, SVIDERSKAYA EV and HUME AN, 2014. Myosin-va and dynamic actin oppose microtubules to drive long-range organelle transport. Current biology : CB. 24(15), 1743-50 HUME AN and SEABRA MC, 2014. Melanoma goes on a diet to get moving: toning down phagocytic Rab7 expression helps melanoma to metastasise. Pigment cell & melanoma research. (In Press.) HUME AN, 2014. Myosin-V - a monarch of pigment transport. Pigment cell & melanoma research. (In Press.) SINGH RK, FURZE RC, BIRRELL MA, RANKIN SM, HUME AN and SEABRA MC, 2014. A role for Rab27 in neutrophil chemotaxis and lung recruitment. BMC cell biology. 15, 39 SINGH, R.K., LIAO, W., TRACEY-WHITE, D., RECCHI, C., TOLMACHOVA, T., RANKIN, S.M., HUME, A.N. and SEABRA, M.C., 2012. Rab27a-mediated protease release regulates neutrophil recruitment by allowing uropod detachment Journal of Cell Science. 125(7), 1652-1656 HUME AN, JOHN A, AKAWI NA, AL-AWADHI AM, AL-SUWAIDI SS, AL-GAZALI L and ALI BR, 2012. Retention in the endoplasmic reticulum is the underlying mechanism of some hereditary haemorrhagic telangiectasia type 2 alk1 missense mutations. Molecular and cellular biochemistry. (In Press.) BOOTH AEG, SEABRA MC and HUME AN, 2012. Rab27a and melanosomes: a model to investigate the membrane targeting of Rabs. Biochemical Society transactions. 40(6), 1383-8 SINGH RK, MIZUNO K, WASMEIER C, WAVRE-SHAPTON ST, RECCHI C, CATZ SD, FUTTER C, TOLMACHOVA T, HUME AN and SEABRA MC, 2012. Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion. The FEBS journal. (In Press.) TARAFDER, ABUL K, WASMEIER, CHRISTINA, FIGUEIREDO, ANA C, BOOTH, ANTONIA E G, ORIHARA, ASUMI, RAMALHO, JOSE S, HUME, ALISTAIR N and SEABRA, MIGUEL C, 2011. Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding. Traffic (Copenhagen, Denmark). 12(8), 1056-66 CHIANG, LILIAN, NGO, JULIE, SCHECHTER, JOEL E, KARVAR, SERHAN, TOLMACHOVA, TANYA, SEABRA, MIGUEL C, HUME, ALISTAIR N and HAMM-ALVAREZ, SARAH F, 2011. Rab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland. American journal of physiology. Cell physiology. 301(2), C507-21 HUME, ALISTAIR N and SEABRA, MIGUEL C, 2011. Melanosomes on the move: a model to understand organelle dynamics. Biochemical Society transactions. 39(5), 1191-6 HUME, A.N., WILSON, M.S., USHAKOV, D.S., FERENCZI, M.A. and SEABRA, M.C., 2011. Semi-automated analysis of organelle movement and membrane content: understanding rab-motor complex transport function Traffic. 12(12), 1686-1701 BOLASCO, GIULIA, TRACEY-WHITE, DHANI C, TOLMACHOVA, TANYA, THORLEY, ANDREW J, TETLEY, TERESA D, SEABRA, MIGUEL C and HUME, ALISTAIR N, 2011. Loss of Rab27 function results in abnormal lung epithelium structure in mice. American journal of physiology. Cell physiology. 300(3), C466-76 HENDRIX A and HUME AN, 2011. Exosome Signaling In Mammary Gland Development And Cancer. The International Journal Of Developmental Biology. 55(7-9), 879-87 HUME, AN and SEABRA, MC, 2011. Melanosomes On The Move: A Model To Understand Organelle Dynamics Biochemical Society Transactions. 39, 1191-1196 ALI BR, NOUVEL I, LEUNG KF, HUME AN, SEABRA MC., 2010. A novel statin-mediated “prenylation block-and-release” assay provides insight into the membrane targeting mechanisms of small GTPases. Biochem Biophys Res Commun. 397, 34-41 OSTROWSKI, M., CARMO, N.B., KRUMEICH, S., FANGET, I., RAPOSO, G., SAVINA, A., MOITA, C.F., SCHAUER, K., HUME, A.N., FREITAS, R.P., GOUD, B., BENAROCH, P., HACOHEN, N., FUKUDA, M. and DESNOS, C., 2010. Rab27a and Rab27b control different steps of the exosome secretion pathway Nature Cell Biology. 12(1), 19-30 RAMALHO JS, LOPES VS, TARAFDER AK, SEABRA MC, HUME AN, 2009. Myosin and Rab linking protein, Myrip, activates MyoVa and MyoVIIa via distinct domains in melanosome transport. Pigment Cell Melanoma Res.. 22, 461-73 HUME, A.N., BUTTGEREIT, J., AL-AWADHI, A,M., AL-SUWAIDI, S.S., JOHN, A., BADER, M., SEABRA, M.C., AL-GAZALI, L. and ALI, B.R., 2009. Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying acromesomelic dysplasia-type Maroteaux Human Molecular Genetics. 18(2), 267-277 NIGHTINGALE TD, PATTNI K, HUME AN, SEABRA MC, CUTLER DF., 2009. Rab27a and Myrip regulate the amount and multimeric state of vWF released from endothelial cells. Blood. 113, 5010-8 WASMEIER C, HUME AN, BOLASCO G, SEABRA MC., 2008. Melanosomes at a glance. J Cell Sci.. 121, 3995-9 HUME, AN, USHAKOV, DS, TARAFDER, AK, FERENCZI, MA and SEABRA, MC, 2007. Rab27a And Myova Are The Primary Miph Interactors Regulating Melanosome Transport In Melanocytes Journal Of Cell Science. 120(17), 3111-3122

近期论文