赵德鹏

个人简介

教育经历2007.09 - 2012.07 兰州大学，博士，导师：王锐 教授2003.09 - 2007.07 兰州大学，学士 工作经历2017.05 - 至今 中山大学药学院，教授2012.09 - 2017.02 荷兰格罗宁根大学，博士后，合作导师：Ben L. Feringa (2016诺贝尔化学奖得主)

个人简介

研究领域

化学能驱动分子机器的设计合成。 多肽药物与手性药物的研发。 光控分子开关以及超分子催化体系的设计。

研究领域

专业：

研究方向：

研究领域和兴趣：

近期论文

1) Depeng Zhao, Thomas van Leeuwen, Jinling Cheng, Ben L. Feringa*, Dynamic Control of Chirality and Self-Assembly of Double–Stranded Helicates with Light, Nature Chemistry, 2017, 9, 250-256. 2) Depeng Zhao, Thomas M. Neubauer, and Ben L. Feringa*, Dynamic Control of Chirality in Phosphine Ligands for Enantioselective Catalysis, Nature Communications, 2015, 6652. 3) Depeng Zhao, Linqing Wang, Dongxu Yang, Yixin Zhang and Rui Wang*, Highly Diastereo- and Enantioselective Synthesis of α-Alkyl Norstatine Derivatives: Catalytic Asymmetric Mannich Reactions of 5H-Oxazol-4-ones, Angew. Chem. Int. Ed., 2012, 51, 7523 –7527. 4) Depeng Zhao, Dongxu Yang, Yijie Wang, Yuan Wang, Linqing Wang, Lijuan Mao and Rui Wang*, Enantioselective Mannich reaction of a highly reactive Horner–Wadsworth–Emmons reagent with imines catalyzed by a bifunctional thiourea, Chem. Sci., 2011, 2, 1918-1921. 5) Depeng Zhao, Martín Fañanás-Mastral, Mu-Chieh Chang, Edwin Otten, and Ben L. Feringa*, Asymmetric Synthesis of N,O-Heterocycles Derivatives via Iridium-Catalysed Intramolecular Enantioselective Allylic Substitution with Amides, Chem. Sci., 2014, 5,4216-4220. 6) Depeng Zhao, and Rui Wang*, Recent Developments in Metal Catalyzed Asymmetric Addition of Phosphorus Nucleophiles, Chem. Soc. Rev., 2012, 41, 2095-2108. 7) Depeng Zhao, Lijuan Mao, Linqing Wang, Dongxu Yang, and Rui Wang*, Catalytic Asymmetric Construction of Tetrasubstituted Carbon Stereocenters by Conjugate Addition of Dialkyl Phosphine Oxides to β,β-Disubstituted α,β-Unsaturated Carbonyl Compounds, Chem. Commun., 2012, 48, 889–891. 8) Depeng Zhao, Lijuan Mao, Yuan Wang, Dongxu Yang, Quanliang Zhang, and Rui Wang*, Catalytic Asymmetric Hydrophosphinylation of α,β-Unsaturated N-Acylpyrroles: Application of Dialkyl Phosphine Oxides in Enantioselective Synthesis of Chiral Phosphine Oxides or Phosphines, Org. Lett. 2010, 12, 1880-1882. 9) Depeng Zhao, Lijuan Mao, Dongxu Yang, and Rui Wang*, Zinc-Mediated Asymmetric Additions of Dialkylphosphine Oxides to α,β-Unsaturated Ketones and N-Sulfinylimines, J. Org. Chem., 2010, 75, 6756. 10) Depeng Zhao, Ye Yuan, Albert S. C. Chan, and Rui Wang*, Highly Enantioselective 1,4-Addition of Diethyl Phosphite to Enones Using a Dinuclear Zn Catalyst, Chem. Eur. J., 2009, 15, 2738-2741. 11) Depeng Zhao, Yuan Wang, Lijuan Mao, and Rui Wang*, Highly Enantioselective Conjugate Additions of Phosphites to α,β-Unsaturated N-Acylpyrroles and Imines: A Practical Approach to Enantiomerically Enriched Amino Phosphonates. Chem. Eur. J., 2009, 15, 10983-10987. 12) Depeng Zhao, Linqing Wang, Dongxu Yang, Yixin Zhang and Rui Wang*, Highly Efficient Asymmetric Michael Addition of Diaryl Phosphine Oxides to α,β-Unsaturated N-Acylated Oxazolidin-2-ones, Chem. Asian J., 2012,7, 881-883. 13) Thomas M. Neubauer , Thomas van Leeuwen, Depeng Zhao , Anouk S. Lubbe , Jos C. M. Kistemaker , and Ben L. Feringa*, Asymmetric Synthesis of First Generation Molecular Motors, Org. Lett., 2014, 16 , 4220–4223. 14) Thomas van Leeuwen, G. Henrieke Heideman, Depeng Zhao, Sander J. Wezenberg * and Ben L. Feringa *, In situ control of polymer helicity with a non-covalently bound photoresponsive molecular motor dopant, Chem. Commun., 2017, 53, 6393-6396. 15) Dongxu Yang, Linqing Wang, Fengxia Han, Depeng Zhao, Bangzhi Zhang, Rui Wang*, Direct Site-Specific and Highly Enantioselective γ-Functionalization of Linear α,β-Unsaturated Ketones: Bifunctional Catalytic Strategy, Angew. Chem. Int. Ed., 2013, 52, 6739–6742. 16) Dongxu Yang, Depeng Zhao, Lijuan Mao, Linqing Wang, and Rui Wang*, Copper/DIPEA-Catalyzed, Aldehyde-Induced Tandem Decarboxylation-Coupling of Natural alpha-Amino Acids and Phosphites or Secondary Phosphine Oxides, J. Org. Chem., 2011, 76 , 6426. 17) Dongxu Yang, Linqing Wang, Depeng Zhao, Fengxia Han, Bangzhi Zhang, Rui Wang*, Development of Metal/Organo Catalytic Systems for Direct Vinylogous Michael Reactions to Build Chiral γ,γ-Disubstituted Butenolides. Chem. Eur. J., 2013, 19, 4691–4694. 18) Liang Hong, Wangsheng Sun, Chunxia Liu, Depeng Zhao and Rui Wang*, Chem. Commun., 2010, 46, 2856. 19) Wenjin Yan, Dong Wang, Jingchao Feng, Peng Li, Depeng Zhao, Rui Wang*, Synthesis of N-Alkoxycarbonyl Ketimines Derived from Isatins and Their Application in Enantioselective Synthesis of 3-Aminooxindoles, Org. Lett., 2012, 2512–2515.

近期论文