A 13-year-old schoolgirl was brought to the Neurological Outpatient Clinic by her mother and the following history was obtained. The second child of her parents, the patient was born normally after an uneventful pregnancy and labour. She subsequently passed the usual early milestones of development at average times and commenced attending school at 5 years of age. However, despite repeating a school year on two occasions she was usually at the bottom of a class of 35-40 pupils. Her mother first noticed a reddish, pimply eruption over the patient’ s chin at the age of 8 or9 years and though she tried numerous skin ointments and lotions the eruption persisted and gradually extended to involve the nose and cheeks. The mother was more emotionally embarrassed by this eruption than was the patient herself who appeared little concerned. A dermatologist was consulted when the patient was 12 years old and he informed the parents that not much could be done for the skin condition though he advised a neurological consultation. Nevertheless, no further action was taken by the girl’ s parents; for about 15 months, when a nocturnal seizure occurred, leading to the neurological consultation a few days later. The seizure took place about 4 o’ clock one morning. The parents were awakened by “a half-strangled scream”, and on entering the patient’s bedroom found her lying stiff and unconscious with her teeth clenched and her limbs jerking. This persisted for a minute or two, and then the patient appeared dazed and confused for about an hour and could not speak properly. After this she fell into a deep sleep for several hours. During the seizure the patient had bitten the inside of her cheek and had been incontinent of urine. By lunch time that day the patient said she felt well apart from a slight frontal headache. Enquiries into family history yielded no history of similar skin disorder, seizures or mental defect in the patient’s elder brother, two younger sister, parents or grandparents.

Which of the following can be chosen as the best title of the passage?